send us an inquiry |
LC1207 Caffeinesuitable for use as excipient exp Ph Eur,BP,USP |
Order number | Packaging | Quantity | Price € |
AC28207 | Plastic bottle | 1 kg | inquire |
AC28207 | Fibre carton | 50 kg | inquire |
Product information | |
Grade | Ph Eur,BP,USP |
Synonyms | 7-Methyltheobromine, 1,3,7-Trimethylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione |
Hill Formula | C8H10N4O2 |
HS Code | 2939 30 00 |
EC number | 200-362-1 |
Molar mass | 194.19 g/mol |
EC index number | 613-086-00-5 |
CAS number | 58-08-2 |
Chemical and physical data | |
Ignition temperature | >600 °C |
Solubility | 20 g/l (20 °C) |
Melting point | 235 – 239 °C |
Molar mass | 194.19 g/mol |
Density | 1.23 g/cm3 (18 °C) |
Bulk density | 300 – 600 kg/m3 |
pH value | 5.5 – 6.5 (10 g/l, H2O, 20 °C) |
Vapor pressure | 20 hPa (80 °C) |
Safety information according to GHS | |
Hazard Statement(s) | H301: Toxic if swallowed. |
Signal Word | Danger |
Hazard Pictogram(s) | ![]() |
Storage class | 10 – 13 Other liquids and solids |
WGK | WGK 1 slightly water endangering |
Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
Safety information | |
R Phrase | R 22 Harmful if swallowed. |
Categories of danger | harmful |
Hazard Symbol | ![]() |
Transport information | |
Declaration (transport by sea) IMDG-Code | UN 1544 ALCALOID SALTS, SOLID, N.O.S.(CAFFEINE), 6.1, III |
Declaration (transport by air) IATA-DGR | UN 1544 ALCALOID SALTS, SOLID, N.O.S.(CAFFEINE), 6.1, III |
Toxicological data | |
LD 50 oral | LD50 rat 261 – 381 mg/kg |
LD 50 dermal | LD50 rat > 2000 mg/kg |
Specifications | |
Assay – perchloric acid titration, calculated on dried substance |
98.5 – 101.0 % |
– HPLC | 98.5 – 101.0 % |
Identity | passes test |
Appearance of solution (1 %; water) | passes test |
Acidic substances | passes test |
Sulphate (SO4) | ≤ 0.0500 % |
Heavy metals (as Pb) | ≤ 0.001 % |
Chloroform (HS-GC) | ≤ 60 ppm |
related substances (HPLC, EP) – Highest single impurity |
≤ 0.10 % |
– Sum of all impurities | ≤ 0.1 % |
chromatographic purity (USP) – Highest single impurity |
≤ 0.10 % |
– Sum of all impurities | ≤ 0.1 % |
Theophylline (HPLC) | ≤ 0.10 % |
Other residual solvents (Ph.Eur./USP/ICH) | excluded by production process |
Sulfated ash | ≤ 0.1 % |
Loss on drying (105 °C) | ≤ 0.5 % |
![]() |