send us an inquiry

LC1207 Caffeine

suitable for use as excipient exp Ph Eur,BP,USP

 

Order number Packaging Quantity Price €
AC28207 Plastic bottle 1 kg inquire
AC28207 Fibre carton 50 kg inquire

 

Product information
Grade Ph Eur,BP,USP
Synonyms 7-Methyltheobromine, 1,3,7-Trimethylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Hill Formula C8H10N4O2
HS Code 2939 30 00
EC number 200-362-1
Molar mass 194.19 g/mol
EC index number 613-086-00-5
CAS number 58-08-2

 

Chemical and physical data
Ignition temperature >600 °C
Solubility 20 g/l (20 °C)
Melting point 235 – 239 °C
Molar mass 194.19 g/mol
Density 1.23 g/cm3 (18 °C)
Bulk density 300 – 600 kg/m3
pH value 5.5 – 6.5 (10 g/l, H2O, 20 °C)
Vapor pressure 20 hPa (80 °C)

 

Safety information according to GHS
Hazard Statement(s) H301: Toxic if swallowed.
Signal Word Danger
Hazard Pictogram(s)
Storage class 10 – 13 Other liquids and solids
WGK WGK 1 slightly water endangering
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

 

Safety information
R Phrase R 22
Harmful if swallowed.
Categories of danger harmful
Hazard Symbol Harmful

 

Transport information
Declaration (transport by sea) IMDG-Code UN 1544 ALCALOID SALTS, SOLID, N.O.S.(CAFFEINE), 6.1, III
Declaration (transport by air) IATA-DGR UN 1544 ALCALOID SALTS, SOLID, N.O.S.(CAFFEINE), 6.1, III

 

Toxicological data
LD 50 oral LD50 rat 261 – 381 mg/kg
LD 50 dermal LD50 rat > 2000 mg/kg

 

Specifications
Assay
– perchloric acid titration, calculated on dried substance
98.5 – 101.0 %
– HPLC 98.5 – 101.0 %
Identity passes test
Appearance of solution (1 %; water) passes test
Acidic substances passes test
Sulphate (SO4) ≤ 0.0500 %
Heavy metals (as Pb) ≤ 0.001 %
Chloroform (HS-GC) ≤ 60 ppm
related substances (HPLC, EP)
– Highest single impurity
≤ 0.10 %
– Sum of all impurities ≤ 0.1 %
chromatographic purity (USP)
– Highest single impurity
≤ 0.10 %
– Sum of all impurities ≤ 0.1 %
Theophylline (HPLC) ≤ 0.10 %
Other residual solvents (Ph.Eur./USP/ICH) excluded by production process
Sulfated ash ≤ 0.1 %
Loss on drying (105 °C) ≤ 0.5 %

 

Caffeine, Laboratory chemicals,  Laboratory Chemicals manufacturer, Laboratory chemicals india,  Laboratory Chemicals directory, elabmart