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LC1414 Cocarboxylase chloride

thiamine diphosphoric acid ester chloride, suitable for use as an active pharmaceutical ingredient api

 

Order number Packaging Quantity Price €
AC28414 Plastic bottle 1 kg Inquire
AC28414 Plastic bottle 5 kg Inquire

 

Product information
Synonyms Thiaminium diphosphoric acid ester chloride, Thiaminium pyrophosphate chloride, Thiaminium pyrophosphoric acid ester chloride, TPP
Hill Formula C12H19ClN4O7P2S
HS Code 2936 22 00
EC number 205-836-1
Molar mass 460.77 g/mol
CAS number 154-87-0

 

Chemical and physical data
Solubility 220 g/l (20 °C)
Melting point 240 – 244 °C (decomposition)
Molar mass 460.77 g/mol
Bulk density 500 kg/m3
pH value 1.0 – 1.4 (100 g/l, H2O, 20 °C)

 

Safety information according to GHS
Storage class 10 – 13 Other liquids and solids
WGK WGK 1 slightly water endangering

 

Specifications
Assay (HPLC, calc. on dried substance) ≥ 93.0 %
Identity (IR-spectrum) passes test
Appearance of solution (10 %; water) passes test
pH-value (10 %; water) 1.0 – 1.4
Chloride (Cl) (calculated on dried substance) 7.5 – 7.9 %
Free phosphate (PO4) ≤ 1.0 %
Sulphate (SO4) ≤ 0.01 %
Heavy metals (as Pb) ≤ 0.001 %
As (Arsenic) ≤ 0.0003 %
Thiamin Monophosphoric Acid Ester Chloride (HPLC) ≤ 4.0 %
Thiamin Dichloride (HPLC) ≤ 0.5 %
Related substances (HPLC) ≤ 1.5 %
Loss on drying (130 °C) ≤ 1.5 %
Residual solvents (Ph.Eur./USP/ICH) class 2 (Methanol) ≤ 2.0 %
Other residual solvents (Ph. Eur./USP/ICH) excluded by manufacturing process
Endotoxins ≤ 12 I.U./g
Microbiological test passes test
Colony count
– aerobic bacteria
≤ 500 CFU/g
– Yeasts and moulds ≤ 100 CFU/g
Salmonella species In 10g substance not detectable
E.coli In 1g substance not detectable
Staphylococcus aureus In 1g substance not detectable
Pseudomonas aeruginosa In 1g substance not detectable
Candida albicans In 1g substance not detectable

 

Cocarboxylase chloride, Laboratory chemicals, Laboratory Chemicals manufacturer, Laboratory chemicals india, Laboratory Chemicals directory, elabmart