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LC1964 Ethyl 4-aminobenzoate (benzocaine),suitable for use as an active pharmaceutical ingredient EMPROVE api Ph Eur,BP,USP |
| Order number | Packaging | Quantity | Price € |
| AC28964 | Glass bottle | 1 kg | Inquire |
| AC28964 | Glass bottle | 50 kg | Inquire |
| Product information | |
| Grade | Ph Eur,BP,USP |
| Synonyms | Benzocaine, 4-Aminobenzoic acid ethyl ester, Aethoform |
| Hill Formula | C9H11NO2 |
| HS Code | 2922 49 85 |
| EC number | 202-303-5 |
| Molar mass | 165.19 g/mol |
| CAS number | 94-09-7 |
| Chemical and physical data | |
| Ignition temperature | >450 °C |
| Solubility | 0.4 g/l (25 °C) |
| Melting point | 89 – 92 °C |
| Molar mass | 165.19 g/mol |
| Bulk density | 320 kg/m3 |
| Boiling point | 172 °C (17.3 hPa) |
| Flash point | 112 °C |
| Safety information according to GHS | |
| Storage class | H317: May cause an allergic skin reaction. |
| Precautionary Statement(s) | P280: Wear protective gloves. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. |
| Signal Word | Warning |
| Hazard Pictogram(s) |  |
| Storage class | 10 – 13 Other liquids and solids |
| WGK | WGK 2 water endangering |
| Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
| Safety information | |
| R Phrase | R 43 May cause sensitization by skin contact. |
| S Phrase | S 24/25-37 Avoid contact with skin and eyes.Wear suitable gloves. |
| Categories of danger | sensitizing |
| Hazard Symbol |  Irritant |
| Toxicological data | |
| LD 50 oral | LD50 rat 3042 mg/kg |
| Specifications | |
| Assay Ph Eur/BP (calculated on dried substance) | 99.0 – 101.0 % |
| Assay USP | 99.0 – 101.0 % |
| Identity | passes test |
| Appearance of solution | passes test |
| Acidity or alkalinity | passes test |
| Melting range – lower value |
≥ 89 °C |
| – upper value | ≤ 92 °C |
| Chloride (Cl) | conforms |
| Heavy metals (as Pb) | ≤ 0.001 % |
| Readily carbonisable substance | passes test |
| Methyl-4-aminobenzoate (HPLC) | ≤ 0.10 % |
| Sum of all impurities (HPLC) | ≤ 0.50 % |
| Residual solvents (Ph.Eur./USP/ICH) class 3 | ≤ 0.5 % |
| Other residual solvents (Ph.Eur./USP/ICH) | excluded by manufactoring process |
| Ordinary impurities (TLC) | passes test |
| Sulfated ash | ≤ 0.1 % |
| Loss on drying | ≤ 0.5 % |
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