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LC317 L-Argininesuitable for use as excipient exp Ph Eur,USP |
| Order number | Packaging | Quantity | Price € |
| AC27317 | Plastic bottle | 1 kg | inquire |
| AC27317 | Plastic drum | 10 kg | inquire |
| Product information | |
| Grade | Ph Eur,USP |
| Hill Formula | C6H14N4O2 |
| HS Code | 2925 29 00 |
| EC number | 200-811-1 |
| Molar mass | 174.2 g/mol |
| CAS number | 74-79-3 |
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Chemical and physical data |
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| Solubility | 148.7 g/l (20 °C) |
| Melting point | 238 °C (decomposition) |
| Molar mass | 174.2 g/mol |
| Bulk density | 640 kg/m3 |
| pH value | 11.4 (100 g/l, H2O, 20 °C) |
| Safety information according to GHS | |
| Hazard Statement(s) | H319: Causes serious eye irritation. |
| Precautionary Statement(s) | P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Signal Word | Warning |
| Hazard Pictogram(s) |  |
| RTECS | CF1934200 |
| Storage class | 10 – 13 Other liquids and solids |
| Categories of danger | NWG not water endangering |
| Categories of danger | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
| Safety information | |
| R Phrase | R 36 Irritating to eyes. |
| S Phrase | S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Categories of danger | irritant |
| Hazard Symbol |  irritant |
| Toxicological data | |
| LD 50 oral | LD50 rat > 5110 mg/kg |
| Specifications | |
| Assay (perchloric acid titration, calculated on dried substance) | 98.5 – 101.0 % |
| Identity (IR-spectrum) | passes test |
| Appearance | white to almost white, fine-grain powder or colorless crystals |
| Appearance of solution (50 g/l; water) | clear and not more intense in color than reference solution BY6 |
| Spec. rotation – α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance |
+25.5° to +28.5° |
| – α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance | +26.3° to +27.7° |
| Chloride (Cl) | ≤ 0.02 % |
| Sulfate (SO4) | ≤ 0.03 % |
| Heavy metals (as Pb) | ≤ 0.001 % |
| Fe (Iron) | ≤ 0.001 % |
| NH4 (Ammonium) | ≤ 0.02 % |
| Ninhydrin – positive substances (total (TLC)) | ≤ 0.5 % |
| Residual solvents (Ph. Eur./USP/ICH) | excluded by manufacturing process |
| Organic volatile impurities (according to USP) | conforms |
| Sulfated ash (600 °C) | ≤ 0.1 % |
| Loss on drying (105 °C; 3 h) | ≤ 0.5 % |
| Bacterial endotoxins | ≤ 2.0 I.U./g |
| Corresponds to Ph. Eur., USP. | |
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