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LC317 L-Arginine

suitable for use as excipient exp Ph Eur,USP

 

Order number Packaging Quantity Price €
AC27317 Plastic bottle 1 kg inquire
AC27317 Plastic drum  10 kg inquire

 

Product information
Grade Ph Eur,USP
Hill Formula C6H14N4O2
HS Code 2925 29 00
EC number 200-811-1
Molar mass 174.2 g/mol
CAS number 74-79-3

 

Chemical and physical data

Solubility 148.7 g/l (20 °C)
Melting point 238 °C (decomposition)
Molar mass 174.2 g/mol
Bulk density 640 kg/m3
pH value 11.4 (100 g/l, H2O, 20 °C)

 

Safety information according to GHS
Hazard Statement(s) H319: Causes serious eye irritation.
Precautionary Statement(s) P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal Word Warning
Hazard Pictogram(s)
RTECS CF1934200
Storage class 10 – 13 Other liquids and solids
Categories of danger NWG not water endangering
Categories of danger 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

 

Safety information
R Phrase R 36
Irritating to eyes.
S Phrase S 26
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Categories of danger irritant
Hazard Symbol irritant

 

Toxicological data
LD 50 oral LD50 rat > 5110 mg/kg

 

Specifications
Assay (perchloric acid titration, calculated on dried substance) 98.5 – 101.0 %
Identity (IR-spectrum) passes test
Appearance white to almost white, fine-grain powder or colorless crystals
Appearance of solution (50 g/l; water) clear and not more intense in color than reference solution BY6
Spec. rotation
– α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance
+25.5° to +28.5°
– α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance +26.3° to +27.7°
Chloride (Cl) ≤ 0.02 %
Sulfate (SO4) ≤ 0.03 %
Heavy metals (as Pb) ≤ 0.001 %
Fe (Iron) ≤ 0.001 %
NH4 (Ammonium) ≤ 0.02 %
Ninhydrin – positive substances (total (TLC)) ≤ 0.5 %
Residual solvents (Ph. Eur./USP/ICH) excluded by manufacturing process
Organic volatile impurities (according to USP) conforms
Sulfated ash (600 °C) ≤ 0.1 %
Loss on drying (105 °C; 3 h) ≤ 0.5 %
Bacterial endotoxins ≤ 2.0 I.U./g
Corresponds to Ph. Eur., USP.

 

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