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LC2986 L-Histidinesuitable for use as excipient EMPROVE exp Ph Eur, |
Order number | Packaging | Quantity | Price € |
AC29986 | Plastic bottle | 100 g | inquire |
AC29986 | Plastic bottle | 1 kg | inquire |
AC29986 | Plastic bottle | 10 kg | inquire |
Product information | |
Grade | Ph Eur,USP |
Hill Formula | C6H9N3O2 |
HS Code | 2933 29 90 |
EC number | 200-745-3 |
Molar mass | 155.16 g/mol |
CAS number | 71-00-1 |
Chemical and physical data | |
Solubility | 38.2 g/l (20 °C) |
Melting point | 272 – 273 °C (decomposition) |
Molar mass | 155.16 g/mol |
Bulk density | 430 kg/m3 |
pH value | 7.7 (10 g/l, H2O, 20 °C) |
Safety information | |
RTECS | MS3070000 |
Storage class | 10 – 13 Other liquids and solids |
WGK | NWG not water endangering |
Toxicological data | |
LD 50 oral | LD50 rat > 5110 mg/kg |
Specifications | |
Assay – acidimetric, calculated on dried substance |
98.5 – 101.0 % |
– perchloric acid titration, calculated on dried substance | 98.5 – 101.5 % |
Identity (IR-spectrum) | passes test |
Appearance | white to almost white fine-crystalline powder or colorless crystals |
Appearance of solution (50 g/l; water) | clear and not more intense in color than reference solution BY7. |
Spec. rotation – α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance |
+11.4° to +12.4° |
– α 25/D, 110 g/l, hydrochloric acid 6 mol/l, calc. on dried substance | +12.6° to +14.0° |
pH (20 g/l, CO2-free water) | 7.0 – 8.5 |
Chloride (Cl) | ≤ 0.02 % |
Sulfate (SO4) | ≤ 0.03 % |
Heavy metals (as Pb) | ≤ 0.001 % |
Fe (Iron) | ≤ 0.001 % |
NH4 (Ammonium) | ≤ 0.02 % |
Ninhydrin – positive substances (total (TLC)) | ≤ 0.5 % |
Residual solvents (Ph. Eur./USP/ICH) | excluded by manufacturing process |
Sulfated ash (600 °C) | ≤ 0.1 % |
Loss on drying (105 °C; 3 h) | ≤ 0.2 % |
Bacterial endotoxins | ≤ 2.0 I.U./g |
Corresponds to Ph. Eur., USP |
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C6H9N3O2