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LC2986 L-Histidinesuitable for use as excipient EMPROVE exp Ph Eur, |
| Order number | Packaging | Quantity | Price € |
| AC29986 | Plastic bottle | 100 g | inquire |
| AC29986 | Plastic bottle | 1 kg | inquire |
| AC29986 | Plastic bottle | 10 kg | inquire |
| Product information | |
| Grade | Ph Eur,USP |
| Hill Formula | C6H9N3O2 |
| HS Code | 2933 29 90 |
| EC number | 200-745-3 |
| Molar mass | 155.16 g/mol |
| CAS number | 71-00-1 |
| Chemical and physical data | |
| Solubility | 38.2 g/l (20 °C) |
| Melting point | 272 – 273 °C (decomposition) |
| Molar mass | 155.16 g/mol |
| Bulk density | 430 kg/m3 |
| pH value | 7.7 (10 g/l, H2O, 20 °C) |
| Safety information | |
| RTECS | MS3070000 |
| Storage class | 10 – 13 Other liquids and solids |
| WGK | NWG not water endangering |
| Toxicological data | |
| LD 50 oral | LD50 rat > 5110 mg/kg |
| Specifications | |
| Assay – acidimetric, calculated on dried substance |
98.5 – 101.0 % |
| – perchloric acid titration, calculated on dried substance | 98.5 – 101.5 % |
| Identity (IR-spectrum) | passes test |
| Appearance | white to almost white fine-crystalline powder or colorless crystals |
| Appearance of solution (50 g/l; water) | clear and not more intense in color than reference solution BY7. |
| Spec. rotation – α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance |
+11.4° to +12.4° |
| – α 25/D, 110 g/l, hydrochloric acid 6 mol/l, calc. on dried substance | +12.6° to +14.0° |
| pH (20 g/l, CO2-free water) | 7.0 – 8.5 |
| Chloride (Cl) | ≤ 0.02 % |
| Sulfate (SO4) | ≤ 0.03 % |
| Heavy metals (as Pb) | ≤ 0.001 % |
| Fe (Iron) | ≤ 0.001 % |
| NH4 (Ammonium) | ≤ 0.02 % |
| Ninhydrin – positive substances (total (TLC)) | ≤ 0.5 % |
| Residual solvents (Ph. Eur./USP/ICH) | excluded by manufacturing process |
| Sulfated ash (600 °C) | ≤ 0.1 % |
| Loss on drying (105 °C; 3 h) | ≤ 0.2 % |
| Bacterial endotoxins | ≤ 2.0 I.U./g |
| Corresponds to Ph. Eur., USP | |
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C6H9N3O2