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LC2989 L-Histidine monohydrochloride monohydratesuitable for use as excipient EMPROVE exp Ph Eur,BP |
| Order number | Packaging | Quantity | Price € |
| AC29989 | Plastic bottle | 500 g | inquire |
| Product information | |
| Grade | Ph Eur,BP |
| Hill Formula | C6H9N3O2 * ClH * H2O |
| HS Code | 2933 29 90 |
| EC number | 211-438-9 |
| Molar mass | 209.64 g/mol |
| CAS number | 5934-29-2 |
| Chemical and physical data | |
| Solubility | 169.9 g/l (20 °C) |
| Melting point | 259 °C (decomposition) |
| Molar mass | 209.64 g/mol |
| Bulk density | 770 kg/m3 |
| pH value | 3.5 – 4.5 (100 g/l, H2O, 20 °C) |
| Safety information | |
| RTECS | MS3119000 |
| Storage class | 10 – 13 Other liquids and solids |
| WGK | WGK 1 slightly water endangering |
| Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
| Specifications | |
| Assay (alkalimetric, calculated on dried substance) | 98.5 – 101.0 % |
| Identity – IR-spectrum |
passes test |
| – chloride | passes test |
| Appearance | white to almost white crystalline powder or colorless crystals |
| Appearance of solution (50 g/l CO2-free water) | clear and not more intense in color than reference solution BY6 |
| pH (50 g/l CO2-free water) | 3.0 – 5.0 |
| Spec. rotation (α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance) | +9.2° to +10.6° |
| Sulfate (SO4) | ≤ 0.03 % |
| Heavy metals (as Pb) | ≤ 0.001 % |
| Fe (Iron) | ≤ 0.001 % |
| NH4 (Ammonium) | ≤ 0.02 % |
| Ninhydrin – positive substances (TLC) | ≤ 0.5 % |
| Residual solvents (Ph. Eur./ICH) | excluded by manufacturing process |
| Sulfated ash (600 °C) | ≤ 0.1 % |
| Loss on drying (150 °C) | 7.0 – 10.0 % |
| Corresponds to Ph. Eur., BP | |
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Loss on drying (105 °C; 3 h)