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LC4063 Methyl 4-hydroxybenzoatesuitable for use as excipient exp Ph Eur,BP,JP,NF,FCC,E 218 |
| Order number | Packaging | Quantity | Price € |
| AC31063 | Fibre carton | 5 kg | inquire |
| AC31063 | Double PE Sack | 20 kg | inquire |
| Product information | |
| Grade | Ph Eur,BP,JP,NF,FCC,E 218 |
| Synonyms | Methylparaben, 4-Hydroxybenzoic acid methyl ester |
| Hill Formula | C8H8O3 |
| Chemical formula | 4-(OH)C6H4(COOCH3) |
| HS Code | 2918 29 00 |
| EC number | 202-785-7 |
| Molar mass | 152.15 g/mol |
| CAS number | 99-76-3 |
| Chemical and physical data | |
| Ignition temperature | >600 °C |
| Solubility | 2.5 g/l (25 °C) |
| Melting point | 125 – 128 °C |
| Molar mass | 152.15 g/mol |
| Bulk density | 300 – 400 kg/m3 |
| pH value | ca.5.8 (H2O, 20 °C) (saturated solution) |
| Vapor pressure | 0.000005 hPa (20 °C) |
| Flash point | 168 °C |
| Safety information | |
| RTECS | DH2450000 |
| Storage class | 10 – 13 Other liquids and solids |
| WGK | WGK 1 slightly water endangering |
| Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
| Transport information | |
| Declaration (transport by sea) IMDG-Code | No Dangerous Good |
| Declaration (transport by air) IATA-DGR | No Dangerous Good |
| Toxicological data | |
| LD 50 oral | LD50 rat 2100 mg/kg |
| Specifications | |
| Assay – acidimetric; calculated on dried substance |
99.5 – 100.5 % |
| – HPLC | conforms |
| Identity | passes test |
| Appearance of solution | passes test |
| Acidic substances | passes test |
| Melting range – lower value |
≥ 125 °C |
| – upper value | ≤ 128 °C |
| Heavy metals (as Pb) | ≤ 0.001 % |
| As (Arsenic) | ≤ 0.0003 % |
| Cd (Cadmium) | ≤ 0.001 % |
| Cu (Copper) | ≤ 0.001 % |
| Hg (Mercury) | ≤ 0.0001 % |
| Pb (Lead) | ≤ 0.0005 % |
| Zn (Zinc) | ≤ 0.001 % |
| Related substances (HPLC) | conforms |
| p-Hydroxy benzoic acid | ≤ 0.5 % |
| Sum of all impurities | ≤ 1.0 % |
| largest unspecified impurity | ≤ 0.5 % |
| Methanol | ≤ 3000 ppm |
| Residual solvents (Ph.Eur./USP/ICH) class 3 | ≤ 0.5 % |
| Other residual solvents (Ph.Eur./USP/ICH) | excluded by manufactoring process |
| Sulfated ash | ≤ 0.05 % |
| Loss on drying (80 °C) | ≤ 0.5 % |
| Corresponds Ph Eur, BP, NF, FCC, E218 | |
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