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LC4063 Methyl 4-hydroxybenzoatesuitable for use as excipient exp Ph Eur,BP,JP,NF,FCC,E 218 |
Order number | Packaging | Quantity | Price € |
AC31063 | Fibre carton | 5 kg | inquire |
AC31063 | Double PE Sack | 20 kg | inquire |
Product information | |
Grade | Ph Eur,BP,JP,NF,FCC,E 218 |
Synonyms | Methylparaben, 4-Hydroxybenzoic acid methyl ester |
Hill Formula | C8H8O3 |
Chemical formula | 4-(OH)C6H4(COOCH3) |
HS Code | 2918 29 00 |
EC number | 202-785-7 |
Molar mass | 152.15 g/mol |
CAS number | 99-76-3 |
Chemical and physical data | |
Ignition temperature | >600 °C |
Solubility | 2.5 g/l (25 °C) |
Melting point | 125 – 128 °C |
Molar mass | 152.15 g/mol |
Bulk density | 300 – 400 kg/m3 |
pH value | ca.5.8 (H2O, 20 °C) (saturated solution) |
Vapor pressure | 0.000005 hPa (20 °C) |
Flash point | 168 °C |
Safety information | |
RTECS | DH2450000 |
Storage class | 10 – 13 Other liquids and solids |
WGK | WGK 1 slightly water endangering |
Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
Transport information | |
Declaration (transport by sea) IMDG-Code | No Dangerous Good |
Declaration (transport by air) IATA-DGR | No Dangerous Good |
Toxicological data | |
LD 50 oral | LD50 rat 2100 mg/kg |
Specifications | |
Assay – acidimetric; calculated on dried substance |
99.5 – 100.5 % |
– HPLC | conforms |
Identity | passes test |
Appearance of solution | passes test |
Acidic substances | passes test |
Melting range – lower value |
≥ 125 °C |
– upper value | ≤ 128 °C |
Heavy metals (as Pb) | ≤ 0.001 % |
As (Arsenic) | ≤ 0.0003 % |
Cd (Cadmium) | ≤ 0.001 % |
Cu (Copper) | ≤ 0.001 % |
Hg (Mercury) | ≤ 0.0001 % |
Pb (Lead) | ≤ 0.0005 % |
Zn (Zinc) | ≤ 0.001 % |
Related substances (HPLC) | conforms |
p-Hydroxy benzoic acid | ≤ 0.5 % |
Sum of all impurities | ≤ 1.0 % |
largest unspecified impurity | ≤ 0.5 % |
Methanol | ≤ 3000 ppm |
Residual solvents (Ph.Eur./USP/ICH) class 3 | ≤ 0.5 % |
Other residual solvents (Ph.Eur./USP/ICH) | excluded by manufactoring process |
Sulfated ash | ≤ 0.05 % |
Loss on drying (80 °C) | ≤ 0.5 % |
Corresponds Ph Eur, BP, NF, FCC, E218 |
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