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LC4064 Methyl 4-hydroxybenzoate sodium saltsuitable for use as excipient exp Ph Eur,BP,NF,E 219 |
| Order number | Packaging | Quantity | Price € |
| AC31064 | Plastic bottle | 5 kg | inquire |
| AC31064 | Double PE Sack | 20 kg | inquire |
| Product information | |
| Grade | Ph Eur,BP,NF,E 219 |
| Synonyms | 4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt |
| Hill Formula | C8H7NaO3 |
| Chemical formula | Na+[4-(O)C6H4(COOCH3)]– |
| HS Code | 2918 29 00 |
| EC number | 225-714-1 |
| Molar mass | 174.13 g/mol |
| CAS number | 5026-62-0 |
| Chemical and physical data | |
| Ignition temperature | >600 °C |
| Solubility | 333 g/l (20 °C) |
| Melting point | >125 °C |
| Molar mass | 174.13 g/mol |
| Bulk density | 700 kg/m3 |
| pH value | 9.7 – 10.3 (1 g/l, H2O) |
| Vapor pressure | (20 °C) |
| Safety information according to GHS | |
| Hazard Statement(s) | H319: Causes serious eye irritation. |
| Precautionary Statement(s) | P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Signal Word | Warning |
| Hazard Pictogram(s) |  |
| Storage class | 10 – 13 Other liquids and solids |
| WGK | WGK 1 slightly water endangering |
| Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
| Safety information | |
| R Phrase | R 36 Irritating to eyes. |
| Categories of danger | irritant |
| Hazard Symbol |  Irritant |
| Transport information | |
| Declaration (transport by sea) IMDG-Code | No Dangerous Good |
| Declaration (transport by air) IATA-DGR | No Dangerous Good |
| Toxicological data | |
| LD 50 oral | LD50 rat > 5000 mg/kg |
| Specifications | |
| Assay – acidimetric, calc. on anhydrous substance |
99.5 – 101.5 % |
| – HPLC, calc.on anhydrous substance | conforms |
| Identity | passes test |
| Appearance of solution | passes test |
| pH-value (0.1 %; water) | 9.5 – 10.5 |
| Chloride (Cl) | ≤ 0.03 % |
| Sulphate (SO4) | ≤ 0.03 % |
| Heavy metals (as Pb) | ≤ 0.001 % |
| As (Arsenic) | ≤ 0.0003 % |
| Cd (Cadmium) | ≤ 0.001 % |
| Cu (Copper) | ≤ 0.001 % |
| Hg (Mercury) | ≤ 0.0001 % |
| Pb (Lead) | ≤ 0.0005 % |
| Zn (Zinc) | ≤ 0.001 % |
| Related substances (HPLC) | conforms |
| p-Hydroxy benzoic acid | ≤ 3.0 % |
| largest unspecified impurity | ≤ 0.5 % |
| Sum of all impurities (without Impurity A of EP) | ≤ 1.0 % |
| Methanol | ≤ 3000 ppm |
| Residual solvents (Ph.Eur./USP/ICH) class 3 | ≤ 0.5 % |
| Other residual solvents (Ph.Eur./USP/ICH) | excluded by manufactoring process |
| Sulfated ash | 39.5 – 44.5 % |
| Water | ≤ 5.0 % |
| Residues of metal catalysts or metal reagents acc. to EMEA/C HMP/SWP/4446/2000 are not likely to be present. | |
| Corresponds Ph Eur, BP,NF,E 219 | |
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