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LC4064 Methyl 4-hydroxybenzoate sodium saltsuitable for use as excipient exp Ph Eur,BP,NF,E 219 |
Order number | Packaging | Quantity | Price € |
AC31064 | Plastic bottle | 5 kg | inquire |
AC31064 | Double PE Sack | 20 kg | inquire |
Product information | |
Grade | Ph Eur,BP,NF,E 219 |
Synonyms | 4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt |
Hill Formula | C8H7NaO3 |
Chemical formula | Na+[4-(O)C6H4(COOCH3)]– |
HS Code | 2918 29 00 |
EC number | 225-714-1 |
Molar mass | 174.13 g/mol |
CAS number | 5026-62-0 |
Chemical and physical data | |
Ignition temperature | >600 °C |
Solubility | 333 g/l (20 °C) |
Melting point | >125 °C |
Molar mass | 174.13 g/mol |
Bulk density | 700 kg/m3 |
pH value | 9.7 – 10.3 (1 g/l, H2O) |
Vapor pressure | (20 °C) |
Safety information according to GHS | |
Hazard Statement(s) | H319: Causes serious eye irritation. |
Precautionary Statement(s) | P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
Signal Word | Warning |
Hazard Pictogram(s) | ![]() |
Storage class | 10 – 13 Other liquids and solids |
WGK | WGK 1 slightly water endangering |
Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
Safety information | |
R Phrase | R 36 Irritating to eyes. |
Categories of danger | irritant |
Hazard Symbol | ![]() |
Transport information | |
Declaration (transport by sea) IMDG-Code | No Dangerous Good |
Declaration (transport by air) IATA-DGR | No Dangerous Good |
Toxicological data | |
LD 50 oral | LD50 rat > 5000 mg/kg |
Specifications | |
Assay – acidimetric, calc. on anhydrous substance |
99.5 – 101.5 % |
– HPLC, calc.on anhydrous substance | conforms |
Identity | passes test |
Appearance of solution | passes test |
pH-value (0.1 %; water) | 9.5 – 10.5 |
Chloride (Cl) | ≤ 0.03 % |
Sulphate (SO4) | ≤ 0.03 % |
Heavy metals (as Pb) | ≤ 0.001 % |
As (Arsenic) | ≤ 0.0003 % |
Cd (Cadmium) | ≤ 0.001 % |
Cu (Copper) | ≤ 0.001 % |
Hg (Mercury) | ≤ 0.0001 % |
Pb (Lead) | ≤ 0.0005 % |
Zn (Zinc) | ≤ 0.001 % |
Related substances (HPLC) | conforms |
p-Hydroxy benzoic acid | ≤ 3.0 % |
largest unspecified impurity | ≤ 0.5 % |
Sum of all impurities (without Impurity A of EP) | ≤ 1.0 % |
Methanol | ≤ 3000 ppm |
Residual solvents (Ph.Eur./USP/ICH) class 3 | ≤ 0.5 % |
Other residual solvents (Ph.Eur./USP/ICH) | excluded by manufactoring process |
Sulfated ash | 39.5 – 44.5 % |
Water | ≤ 5.0 % |
Residues of metal catalysts or metal reagents acc. to EMEA/C HMP/SWP/4446/2000 are not likely to be present. | |
Corresponds Ph Eur, BP,NF,E 219 |
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