send us an inquiry

LC4083 Nicotinamide

for synthesis

 

Order number Packaging Quantity Price €
AC31083 Fibre carton 25 kg inquire

 

Product information
Grade Ph Eur,BP,USP,FCC
Synonyms Nicotinamide, Niacinamide, 3-Pyridinecarboxamide
Hill Formula C6H6N2O
HS Code 2936 29 00
EC number 202-713-4
Molar mass 122.13 g/mol
CAS number 98-92-0

 

Chemical and physical data
Ignition temperature 555 °C
Solubility 1000 g/l (20 °C)
Melting point 128 – 131 °C (sublimed)
Molar mass 122.13 g/mol
Density 1.40 g/cm3
Bulk density 360 kg/m3
pH value 6.0 – 7.5 (50 g/l, H2O, 20 °C)
Boiling point 224 °C (20 hPa)
Flash point 182 °C

 

Safety information according to GHS
Hazard Statement(s) H319: Causes serious eye irritation.
Precautionary Statement(s) P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal Word Warning
Hazard Pictogram(s)
RTECS QS3675000
Storage class 10 – 13 Other liquids and solids
WGK WGK 1 slightly water endangering
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

 

Safety information
R Phrase R 36
Irritating to eyes.
S Phrase S 26
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Categories of danger irritant
Hazard Symbol Irritant

 

Toxicological data
LD 50 oral LD50 rat 3530 – 3540 mg/kg
LD 50 dermal LD50 rabbit > 2000 mg/kg

 

Specifications
Assay
– perchloric acid titration, calculated on dried substance
99.0 – 101.0 %
– HPLC, calc. on dried substance 98.5 – 101.0 %
Identity (IR-spectrum) conforms
Appearance White to almost white, crystalline powder
Appearance of solution (50 g/l; water) Clear, colourless, not more intense in color than reference solution BG7
pH (50 g/l; water) 6.0 – 7.5
Melting range
– lower value
≥ 128 °C
– upper value ≤ 131 °C
Absorption ratio (A 245 nm/A 262 nm) 0.63 – 0.67
Heavy metals (as Pb) ≤ 20 ppm
As (Arsenic) ≤ 3 ppm
Cu (Copper) ≤ 20 ppm
Pb (Lead) ≤ 2 ppm
Zn (Zinc) ≤ 25 ppm
Toluene (HS-GC) ≤ 890 ppm
Other residual solvents (Ph.Eur./USP/ICH) excluded by production process
Readily carbonisable substance conforms
Related substances (DC) ≤ 0.25 %
Nicotinic acid (TLC) ≤ 0.2 %
Sulfated ash (600 °C) ≤ 0.1 %
Loss on drying (Vacuum; 18 h) ≤ 0.5 %
Corresponds to Ph Eur, BP, USP, FCC.