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LC5163 Procaine hydrochloride suitable for use as an active pharmaceutical ingredient |
Order number | Packaging | Quantity | Price € |
AC32163 | Plastic bottle | 1 kg | inquire |
Product information | |
Synonyms | 2-Diethylamino-4-amino-benzoate hydrochloride |
Hill Formula | C13H21ClN2O2 |
Chemical formula | C13H20N2O2 * HCl |
HS Code | 2922 49 85 |
EC number | 200-077-2 |
Molar mass | 272.77 g/mol |
CAS number | 51-05-8 |
Chemical and physical data | |
Solubility | 1000 g/l (20 °C) |
Melting point | 155 – 158 °C |
Molar mass | 272.77 g/mol |
Bulk density | 600 kg/m3 |
pH value | 5.0 – 6.0 (50 g/l, H2O, 20 °C) |
Safety information according to GHS | |
Hazard Statement(s) | H301: Toxic if swallowed. |
Signal Word | Danger |
Hazard Pictogram(s) | ![]() |
Storage class | 6.1A Combustible substances, toxic |
Disposal | 9 Carcinogenic compounds and flammable compounds labelled “Highly toxic” or “Toxic”: container F. Alkyl sulfates are carcinogenic; Take particular care to avoid inhalation and skin contact. To neutralize alkyl sulfates, add dropwise (from a dropping funnel) to concentrated ice-cool Ammonia solution (Cat.No. 105426) with vigorous stirring. Before placing in container D, check the pH with pH Universal indicator strips (Cat.No. 109535) |
Safety information | |
R Phrase | R 25 Toxic if swallowed. |
S Phrase | S 24-37-45 Avoid contact with skin.Wear suitable gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
Categories of danger | toxic |
Hazard Symbol | ![]() |
Transport information | |
Declaration (transport by sea) IMDG-Code | UN 2811 TOXIC SOLID, ORGANIC, N.O.S.(PROCAINE HYDROCHLORIDE), 6.1, III |
Declaration (transport by air) IATA-DGR | UN 2811 TOXIC SOLID, ORGANIC, N.O.S.(PROCAINE HYDROCHLORIDE), 6.1, III |
Toxicological data | |
LD 50 oral | LD50 rat 200 mg/kg |
Specifications | |
Assay (oxidimetrically; calc. on dried substance) | 99.0 – 101.0 % |
Identity | passes test |
Appearance of solution – 5 %; water |
passes test |
– 10 %; water | passes test |
pH-value – 2 %; water |
5.0 – 6.0 |
– 5 %; water | 5.0 – 6.0 |
Acid impurities | passes test |
Melting range – lower value |
≥ 155 °C |
– upper value | ≤ 158 °C |
Heavy metals (as Pb) | ≤ 0.0005 % |
Related substances (TLC) | passes test |
Methanol (HS-GC) | ≤ 3000 ppm |
Toluene (HS-GC) | ≤ 890 ppm |
Residual solvents (Ph.Eur./USP/ICH) class 3 | ≤ 0.5 % |
Other residual solvents (Ph.Eur./USP/ICH) | excluded by production process |
Sulfated ash | ≤ 0.1 % |
Loss on drying (105 °C) | ≤ 0.5 % |
Endotoxine (gel-clot-test) | ≤ 600 I.U./g |
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